OCN Cheat Sheet: High-Yield Oncology Facts

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The numbers and emergencies that recur on the OCN. Skim before test day, then prove it with practice.

Exam facts

  • 165 questions (145 scored), 3 hours
  • Biggest area: Symptom Management & Supportive Care (25%)

Neutropenia & infection

  • ANC = WBC × (% segs + % bands)
  • Severe neutropenia: ANC < 500; greatest risk at the nadir, ~7–14 days post-chemo
  • Febrile neutropenia is an emergency — cultures + antibiotics promptly

Oncologic emergencies to recognize fast

  • Tumor lysis syndrome — ↑K, ↑phosphate, ↑uric acid, ↓calcium
  • Spinal cord compression — new/worsening back pain with neuro changes
  • SVC syndrome — facial/arm swelling, dyspnea
  • Hypercalcemia of malignancy — treat with hydration and bisphosphonates

Chemo safety

  • Vesicant extravasation — stop the infusion, leave the device to aspirate, give antidote if indicated
  • Follow safe-handling precautions for hazardous drugs

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Sources & references

The exam facts on this page are drawn from official certifying-body materials, reviewed 2026-06-18 by the DrCertifications exam-prep team (10+ years in exam preparation and publishing).