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Get a feel for the Neonatal Pediatric Transport exam before you commit. These sample
questions match the NCC C-NPT style — scenario-based, single best answer,
with a rationale that explains the reasoning. Try each before you read the answer.
Unlock 700+ C-NPT practice questions across 4 full-length simulators — $19.99 lifetime →
How close are these to the real C-NPT?
The C-NPT is 125 questions (100 scored, 25 unscored) over 2 hours. It’s weighted toward
Transport Core Knowledge (48%), then neonatal and pediatric transport (26% each). The samples
below cover all three.
Sample C-NPT questions
- During air transport at altitude, a neonate’s small pneumothorax suddenly
enlarges. Which gas law explains this?- A. Dalton’s law
- B. Boyle’s law
- C. Henry’s law
- D. Charles’s law
Answer: B. Boyle’s law — as barometric pressure falls with altitude,
trapped gas expands, so a pneumothorax, bowel gas, or an air-filled ETT cuff all enlarge. This
is core transport physiology, which is why the team monitors for tension pneumothorax in flight. - A duct-dependent congenital heart lesion is suspected in a cyanotic neonate being
transported. Which medication keeps the ductus arteriosus open?- A. Indomethacin
- B. Adenosine
- C. Prostaglandin E1 (alprostadil)
- D. Furosemide
Answer: C. Prostaglandin E1 maintains ductal patency until definitive care.
Indomethacin (A) does the opposite (closes the duct). Apnea is a known PGE1 side effect, so the
team prepares to support the airway. - A cold-stressed neonate on transport is at greatest risk for which complication?
- A. Hyperglycemia and alkalosis
- B. Increased oxygen consumption and metabolic acidosis
- C. Decreased metabolic rate
- D. Hypertension
Answer: B. Cold stress drives up oxygen consumption and glucose use,
producing metabolic acidosis and hypoglycemia. Thermoregulation is a first-line transport
priority — the “T” in the S.T.A.B.L.E. program. - What is the appropriate uncuffed ETT size estimate for a 4-year-old child?
- A. 3.5
- B. 4.5
- C. 5.0
- D. 6.0
Answer: C. Uncuffed ETT ≈ (age/4) + 4 = (4/4) + 4 = 5.0. For a cuffed
tube, subtract about 0.5. Knowing pediatric airway sizing cold is essential on transport. - A 33-week neonate has a transport blood glucose of 32 mg/dL. What is the priority?
- A. Recheck in one hour
- B. Give IV dextrose (e.g., D10) and recheck
- C. Withhold all fluids
- D. Start antibiotics
Answer: B. That’s hypoglycemia in a preterm neonate — treat promptly
with IV dextrose and recheck. “Sugar” is the “S” in S.T.A.B.L.E. and a constant transport concern.
How did you do?
If the physiology felt rusty, that’s what practice fixes. Our bank has 700+ C-NPT questions
across 4 timed simulators with rationales like these, plus a free sample test you can take now.
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Sources & references
The exam facts on this page are drawn from official certifying-body materials, reviewed 2026-06-18 by the DrCertifications exam-prep team (10+ years in exam preparation and publishing).